One obvious difference between Winstrol Depot and other injectables is that it is not esterified, being sold as aqueous stanozolol suspension. (It should not be called water-soluble: virtually none of it is dissolved in the water.) This means that it does not have a classical half-life, where at time x the level is ½ the starting level, at time 2 x the level is ¼, at time 3 x the level is 1/8, etc. Instead, the microcrystals slowly dissolve, and when they have all dissolved levels of the drug then fall very rapidly.

For veterinary application, Upjohn claims that once-weekly doses supply constant levels. I am not sure if that is actually true or not – it might be true in terms of being clinically practical but not literally true. If true, then it may be that the observation of bodybuilders that frequent dosing is required has more to do with a significant dose being required, e.g. 350 mg/week, rather than an actual need for it to be injected daily. Unfortunately bodybuilders often make illogical comparisons, and will conclude that daily injections are needed, since a once a week injection of 50 mg did not do the job! Well, of course it didn’t: the dose was too low. For a future article, some urinalysis testing may be performed to come up with some more specific information on this matter, since it is of interest to many.

In some cases, women have had virilization problems with oral Winstrol at only 2 mg/day. Thus, it cannot be assumed that even a single tab per day is necessarily safe for all women concerned about maintaining their natural voice, avoiding hirsutism, etc.

Stanozolol has some unique biochemical properties which we will discuss in a later article.