Content Mesterolone. Actions Oral androgen for use in men. Indications All disorders due to androgen deficiency, eg reduced efficiency in middle and advanced age, infertility, hypogonadism. Dosage The tablets are to be swallowed whole with some liquid. Reduced Efficiency in Middle and Advanced Age Due to Androgen Deficiency: 1 tab 3 times daily. After a satisfactory clinical improvement, it can be tried to reduce the dose. Hypogonadism Requires Continuous Therapy: Not more than 200 mg daily in 3 divided doses for several months. For further treatment, the dose should be reduced. Infertility: For the improvement of sperm quantity and quality: 50-100 mg/day in 2-3 divided doses with periodical sperm count for follow-up treatment. Contraindications Carcinoma of the prostate, a history of or existing liver tumours. Special Precautions Androgens are not suitable for enhancing muscular development in healthy individuals or for increasing physical ability. Provironum is for use in male patients only. Regular examinations of the prostate should be carried out prophylactically. In rare cases, benign and in even rarer cases malignant liver tumours leading in isolated cases to life-threatening intra-abdominal haemorrhage have been observed after the use of hormonal substances, eg the one contained in Provironum/Proviron. If severe upper abdominal complaints, liver enlargement or signs of intra-abdominal haemorrhage occur, a liver tumour should be included in the differential-diagnostic considerations. Side Effects If, in individual cases, frequent or persistent erections occur, the dose should be reduced or the treatment discontinued in order to avoid injury to the penis.